The PHOCNOSIS project aims at the development and the preclinical validation of a nanotechnology-based handheld point-of-care testing (POCT) analysis device for its application in the early diagnosis of cardiovascular diseases (CVD). The diagnosis will be carried out by means of the fast (<10 minutes), ultra-sensitive (<1 ng/L) and label-free detection of multiple cardiac biomarkers, using a small volume of whole blood (<100 μL). This POCT analysis device will significantly help in the implementation of mass screening programs, with the consequent impact on clinical management, reducing also costs of treatments, and increasing survival rates.
Fraunhofer IZM contributes in PHOCNOSIS by developing the integration and the package of an optofluidic sensing chip.
This work is supported by Horizon 2020 within the objective HEALT-PHC10-2014, project “PHOCNOSIS” with a grant agreement number of 634013.