Minimally Invasive Neuromodulation Implant and implantation procedure based on ground-breaking GRAPHene technology for treating brain disorders

Neurological diseases such as Parkinson's and Alzheimer's have been steadily increasing over the past 25 years, posing a significant burden for both patients and their families. Deep brain stimulation (DBS), commonly referred to as a »brain pacemaker« , has emerged as a promising approach for treating brain disorders that do not respond to conventional medications.

The MINIGRAPH project aims to develop innovative DBS brain implants based on a flexible electronic unit made of biocompatible polymer and high-density graphene microelectrodes. These novel implants allow for optimal adaptation to the shape of the brain and are significantly less invasive and lighter than current solutions. This allows for personalized and adaptive therapies to be implemented. In addition, a minimally invasive implantation procedure with high precision through a small incision in the skull is being developed.

Thus, the MINIGRAPH project represents a significant advancement in the treatment of neurological diseases and could greatly improve the quality of life for many patients.

Wafer-level technology allows entire implant systems to be manufactured on a single 200 nm wafer substrate. By embedding thin chips in interconnection layers, functionality can be optimized while minimizing size, power consumption, and manufacturing costs.

Another crucial aspect is the hermetic sealing, which is achieved, for example, through thin-film encapsulation with biocompatible coatings. This is crucial for performance and biocompatibility and protects the sensitive electronic components from external factors.